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Hodgkin’s Lymphoma

Hodgkin's lymphoma, also known as Hodgkin lymphoma or HL, is a type of cancer that originates in the lymphatic system, a part of the body's immune system. It is characterized by the presence of Reed-Sternberg cells, large abnormal cells that are typically found in Hodgkin's lymphoma tissue.

Causes and Risk Factors:

The exact cause of Hodgkin's lymphoma is unknown, but certain risk factors may increase the likelihood of developing the disease:

  • Age: Hodgkin's lymphoma is most commonly diagnosed in two age groups: young adults (between 15 and 35 years old) and older adults (after the age of 55).
  • Gender: It occurs more frequently in males than in females.
  • Family History: Individuals with a family history of Hodgkin's lymphoma have a slightly higher risk.
  • Weakened Immune System: Having a weakened immune system due to conditions such as HIV/AIDS or immunosuppressive therapy may increase the risk.
  • Epstein-Barr Virus (EBV): Infection with EBV, a member of the herpesvirus family, has been linked to an increased risk, especially in young adults.
  • Personal History of Infectious Mononucleosis: People who have had infectious mononucleosis, often caused by EBV, may have a higher risk.
Symptoms:

Common symptoms of Hodgkin's lymphoma may include:

  • Enlarged Lymph Nodes: Painless swelling, usually in the neck, armpits, or groin.
  • Persistent Fatigue: Tiredness that doesn't improve with rest.
  • Unexplained Weight Loss: Significant and unintentional weight loss.
  • Night Sweats: Profuse sweating, especially at night.
  • Fever: Persistent, unexplained fever.
  • Itchy Skin: Pruritus (itching) without an apparent cause.

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