Hodgkin’s Lymphoma
Hodgkin's lymphoma, also known as Hodgkin lymphoma or HL, is a type of cancer that originates in the lymphatic system, a part of the body's immune system. It is characterized by the presence of Reed-Sternberg cells, large abnormal cells that are typically found in Hodgkin's lymphoma tissue.
Causes and Risk Factors:
The exact cause of Hodgkin's lymphoma is unknown, but certain risk factors may increase the likelihood of developing the disease:
- Age: Hodgkin's lymphoma is most commonly diagnosed in two age groups: young adults (between 15 and 35 years old) and older adults (after the age of 55).
- Gender: It occurs more frequently in males than in females.
- Family History: Individuals with a family history of Hodgkin's lymphoma have a slightly higher risk.
- Weakened Immune System: Having a weakened immune system due to conditions such as HIV/AIDS or immunosuppressive therapy may increase the risk.
- Epstein-Barr Virus (EBV): Infection with EBV, a member of the herpesvirus family, has been linked to an increased risk, especially in young adults.
- Personal History of Infectious Mononucleosis: People who have had infectious mononucleosis, often caused by EBV, may have a higher risk.
Symptoms:
Common symptoms of Hodgkin's lymphoma may include:
- Enlarged Lymph Nodes: Painless swelling, usually in the neck, armpits, or groin.
- Persistent Fatigue: Tiredness that doesn't improve with rest.
- Unexplained Weight Loss: Significant and unintentional weight loss.
- Night Sweats: Profuse sweating, especially at night.
- Fever: Persistent, unexplained fever.
- Itchy Skin: Pruritus (itching) without an apparent cause.